Characteristics of aconitine-induced delayed afterdepolarization.
نویسندگان
چکیده
منابع مشابه
Electrophysiological Characteristics of Arterially-Perfused Canine Pulmonary Veins: Role of the Delayed Afterdepolarization-Induced Triggered Activity
Background and Objectives:The mechanism responsible for the generation of ectopic beats in pulmonary veins (PVs) remains to be well defined. The present study examines the electrophysiological characteristics of the PVs and other regions of the canine left atrium (LA) under low dose (300 μM) caffeine condition. Materials and Methods:Transmembrane action potentials were recorded from the left su...
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Renewed interest in the pharmacological action of aconitine has followed the work of Sherf (1947), Prinzmetal et al. (1950 and 1951), and Brown and Acheson (1952). Its use in experimental medicine produces stimulus formation in the dog's heart with auricular tachycardia and in certain circumstances ventricular tachycardia and fibrillation: it has become a useful tool in the hands of the researc...
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The purpose of this study was to investigate the effects of resveratrol on delayed afterdepolarization (DAD) and triggered activity (TA) induced by ouabain in guinea pig papillary muscles and the underlying mechanism. Action potentials were recorded using intracellular microelectrode technique. The results obtained are as follows: (1) DAD and TA induced by ouabain (1 micromol/L) were inhibited ...
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ژورنال
عنوان ژورنال: Japanese Journal of Electrocardiology
سال: 1985
ISSN: 1884-2437,0285-1660
DOI: 10.5105/jse.5.757